Therapeutic efficacy of different Hemodialysis prescriptions in canine azotemia

Research (Published online: 29-12-2014)

23. Therapeutic efficacy of different Hemodialysis prescriptions in canine azotemia - Ekta Atul Thakkar and Rajiv V. Gaikwad

Veterinary World, 7(12): 1150-1156

   doi: 10.14202/vetworld.2014.1150-1156

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Abstract

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Aim: The aim was to determine therapeutic efficacy of different Hemodialysis prescriptions in canine azotemia.

Materials and Methods: Patients (n=9) with acute onset of renal dysfunction or chronic patients with superimposed acute factor (component) or patients with known chronic nature of the disease were dialyzed with Fresenius 4008S hemodialysis machine after jugular catheterization. Patients were randomly divided into two groups, one group (n=3) was dialyzed every day and second (n=4) was dialyzed on alternate days. The patients were evaluated for following parameters to compare the efficacy of the dialysis prescription: Urea reduction ratio (URR), creatinine reduction ratio (CRR), Kt/V, time averaged concentration of urea (TAC urea).

Result and Discussion: Increasing both dialysis frequency and duration is the superior dialysis schedule. Patient dialyzed every day with total processed blood volume 1.79 L/Kg for 4 h 26 min/session had the lowest TAC of 36.82 mg/dl, thereby was considered it as a better prescription.

Keywords: creatinine reduction ratio, hemodialysis, Kt/V, time averaged concentration of urea, urea reduction ratio.